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Antibacterial Agents - Chemistry Mode Of Action Mechanisms Of Resistance And Clinical Applications (Cód: 9237234)

Anderson,Rosaleen; Groundwater,Paul; Todd,Adam; Worsley,Alan

John Wiley & Sons

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Descrição

Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. 'Antibacterial Agents' is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated 'lab-to-clinic' approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin 'Antibacterial Agents' will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry. 'Antibacterial Agents' is an essential guide to an important class of chemotherapeutic drugs. In this full colour volume, compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. Topics are presented using an integrated 'lab-to-clinic' approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects including links to current guidelines, significant drug interactions, cautions and contraindications, prodrugs and future improvements. This modern text summarises all the current knowledge on antibacterial drugs, and each chapter includes full colour diagrams and a set of key points for easy reference. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-lactam and glycopeptide antibiotics, cycloserine, isoniazid, and daptomycin 'Antibacterial Agents' will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

Características

Produto sob encomenda Sim
Marca John Wiley & Sons
Cód. Barras 9780470972441
Altura 25.15 cm
I.S.B.N. 9780470972441
Profundidade 2.29 cm
Referência 019412653
Acabamento Capa dura
Ano da edição 2012
Idioma Inglês
Número de Páginas 378
Peso 0.98 Kg
Largura 19.30 cm
AutorAnderson,Rosaleen; Groundwater,Paul; Todd,Adam; Worsley,Alan

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