Frete Grátis
  • Google Plus

Chemistry And Application Of H-Phosphonates (Cód: 1635339)

Troev

Elsevier Science

Ooops! Este produto não está mais a venda.
Mas não se preocupe, temos uma versão atualizada para você.

Ooopss! Este produto está fora de linha, mas temos outras opções para você.
Veja nossas sugestões abaixo!

R$ 1.355,90 em até 10x de R$ 135,59 sem juros
Cartão Saraiva R$ 1.288,11 (-5%) em até 1x no cartão ou em até 12x de R$ 112,99 sem juros
Grátis

Cartão Saraiva
Quer comprar em uma loja física? Veja a disponibilidade deste produto
?

Entregas internacionais: Consulte prazos e valores de entrega para regiões fora do Brasil na página do Carrinho.

ou receba na loja com frete grátis

X

* Válido para compras efetuadas em dias úteis até às 18:00, horário de Brasília, com cartão de crédito e aprovadas na primeira tentativa.

Formas de envio Custo Entrega estimada
X Consulte as lojas participantes

Saraiva MegaStore Shopping Eldorado Av. Rebouças, 3970 - 1º piso - Pinheiros CEP: 05402-600 - São Paulo - SP

Descrição

Chemistry and Application of H-Phosphonates is an excellent source for those planning the synthesis of new phosphorus-containing compounds and in particular derivatives containing a phosphonate, phosphoramide or phosphonic acid diester group. The rich chemistry, low cost and easy availability of diesters of H-phosphonic acid makes them an excellent choice as synthone in a number of practically important reactions. Phosphonic acid esters are intermediates in the synthesis of important classes of compounds such as alpha-aminophosphonic acids, bisphosphonates, epoxyalkylphosphonates, alpha-hydroxyalkylphosphonates, phosphoramides, poly(alkylene H-phosphonate)s, poly(alkylene phosphate)s, nucleoside H-phosphonates. The synthesis of each of these compound classes is reviewed in detail.Alpha-Aminophosphonic acids are an important class of biologically active compounds, which have received an increasing amount of attention because they are considered to be structural analogues of the corresponding Alpha-amino acids. The utilities of alpha-aminophosphonates as peptide mimics, haptens of catalytic antibodies, enzyme inhibitors, inhibitors of cancers, tumours, viruses, antibiotics and pharmacologic agents are well documented. Alpha-Hydroxyalkanephosphonates are compounds of significant biological and medicinal applications. Dialkyl epoxyalkylphosphonates are of interest because of their use as intermediates in the synthesis of bioactive substances, and as modifiers of natural and synthetic polymers. Bisphosphonates are drugs that have been widely used in different bone diseases, and have recently been used successfully against many parasites. Poly(alkylene H-phosphonate)s and poly(alkylene phosphate)s are promising, biodegradable, water soluble, new polymer-carriers of drugs. Nucleoside H-phosphonates seem to be the most attractive candidates as starting materials in the chemical synthesis of DNA and RNA fragments. The 5’-hydrogen phosphonate-3’-azido-2’,3’-dideoxythimidine is one of the most significant anti-HIV prodrug, which is currently in clinical trials.Chapters review the synthesis

Características

Produto sob encomenda Sim
Marca Elsevier Science
Cód. Barras 9780444527370
Altura 24.00 cm
I.S.B.N. 9780444527370
Profundidade 2.09 cm
Acabamento Capa dura
Ano da edição 15/9/2006
Idioma Inglês
Número de Páginas 336
Peso 0.69 Kg
Largura 16.50 cm
AutorTroev

Avaliações

Avaliação geral: 0

Você está revisando: Chemistry And Application Of H-Phosphonates

Chemistry And Application Of H-Phosphonates (Cód: 1635339) Chemistry And Application Of H-Phosphonates (Cód: 1635339)
R$ 1.355,90
Chemistry And Application Of H-Phosphonates (Cód: 1635339) Chemistry And Application Of H-Phosphonates (Cód: 1635339)
R$ 1.355,90