Frete Grátis
  • Google Plus
Livro Digital

Evaluation of Enzyme Inhibitors in Drug Discovery (Cód: 9292587)

Copeland,Robert A.

Wiley (Digital)

Ooops! Este produto não está mais a venda.
Mas não se preocupe, temos uma versão atualizada para você.

Ooopss! Este produto está fora de linha, mas temos outras opções para você.
Veja nossas sugestões abaixo!

R$ 197,29 em até 6x de R$ 32,88 sem juros
Cartão Saraiva R$ 187,43 (-5%) em até 1x no cartão ou em até 9x de R$ 21,92 sem juros
Grátis

Cartão Saraiva

Descrição

Offers essential guidance for discovering and optimizing novel drug therapies Using detailed examples, Evaluation of Enzyme Inhibitors in Drug Discovery equips researchers with the tools needed to apply the science of enzymology and biochemistry to the discovery, optimization, and preclinical development of drugs that work by inhibiting specific enzyme targets. Readers will applaud this book for its clear and practical presentations, including its expert advice on best practices to follow and pitfalls to avoid. This Second Edition brings the book thoroughly up to date with the latest research findings and practices. Updates explore additional forms of enzyme inhibition and special treatments for enzymes that act on macromolecular substrates. Readers will also find new discussions detailing the development and application of the concept of drug-target residence time. Evaluation of Enzyme Inhibitors in Drug Discovery begins by explaining why enzymes are such important drug targets and then examines enzyme reaction mechanisms. The book covers: Reversible modes of inhibitor interactions with enzymes Assay considerations for compound library screening Lead optimization and structure-activity relationships for reversible inhibitors Slow binding and tight binding inhibitors Drug-target residence time Irreversible enzyme inactivators The book ends with a new chapter exploring the application of quantitative biochemical principles to the pharmacologic evaluation of drug candidates during lead optimization and preclinical development. The Second Edition of Evaluation of Enzyme Inhibitors in Drug Discovery continues to offer a treatment of enzymology applied to drug discovery that is quantitative and mathematically rigorous. At the same time, the clear and simple presentations demystify the complex science of enzymology, making the book accessible to many fields— from pharmacology to medicinal chemistry to biophysics to clinical medicine.

Características

Produto sob encomenda Sim
Marca Wiley (Digital)
Cód. Barras 9781118540404
Início da Venda 09/03/2016
Territorialidade Internacional
Formato Livro Digital Pdf
Gratuito Não
Proteção Drm Sim
Número da edição 2
Idioma 337
Código do Formato Pdf
Ano da Publicação 113
Peso 0.00 Kg
AutorCopeland,Robert A.

Avaliações

Avaliação geral: 0

Você está revisando: Evaluation of Enzyme Inhibitors in Drug Discovery

Evaluation of Enzyme Inhibitors in Drug Discovery (Cód: 9292587) Evaluation of Enzyme Inhibitors in Drug Discovery (Cód: 9292587)
R$ 197,29
Evaluation of Enzyme Inhibitors in Drug Discovery (Cód: 9292587) Evaluation of Enzyme Inhibitors in Drug Discovery (Cód: 9292587)
R$ 197,29