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e-book

Biochemistry of Collagens, Laminins and Elastin - Structure, Function and Biomarkers (Cód: 9534593)

Morten Karsdal

ELSEVIER S&T

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Biochemistry of Collagens, Laminins and Elastin - Structure, Function and Biomarkers

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Descrição

Biochemistry of Collagens, Laminins, and Elastin: Structure, Function, and Biomarkers provides a comprehensive introduction to collagen and structural proteins. Type I collagen is one of the most abundant molecules in the body, playing essential roles in different tissues, particularly bone and skin. A key aspect of type I collagen is its post-translational modifications which are essential for correct synthesis and structural integrity of collagens, for tissue-specific functionality, as well as for application as biomarkers of different pathologies. This volume summarizes current data on key structural proteins (collagens, laminins and elastin), reviews how these molecules affect pathologies, and describes selected modifications of proteins that result in altered signaling properties of the original extracellular matrix component. Further, it discusses the novel concept that an increasing number of components of the ECM harbor cryptic signaling functions that may be viewed as endocrine functions. Additionally, it highlights how this knowledge can be exploited to modulate fibrotic disease.Provides a comprehensive introduction to collagen and structural proteinsProvides insight into emerging analytical technologies that can detect biomarkers of extracellular matrix degradationIncludes a chapter dedicated to the biomarkers of structural proteinsContains insights into the biochemical interactions and changes to structural composition of proteins in disease states

Características

Peso 0.00 Kg
Produto sob encomenda Sim
Marca ELSEVIER S&T
Número de Páginas 272 (aproximado)
Idioma 337
Acabamento e-book
Territorialidade Internacional
Formato Livro Digital Pdf
Proteção Drm Sim
Tamanho do Arquivo 3336
Início da Venda 29/07/2016
Código do Formato Epub
Cód. Barras 9780128098998
Ano da Publicação 116
AutorMorten Karsdal