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e-book

Regulation of Gastrointestinal Mucosal Growth - Second Edition (Cód: 9453669)

Wang,Jian-ying; Jaladanki,Rao N.

Morgan and Claypool Publishers (Livros Digitais)

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Regulation of Gastrointestinal Mucosal Growth - Second Edition

R$108,00

Descrição

The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.

Características

Peso 0.00 Kg
Produto sob encomenda Sim
Marca Morgan and Claypool Publishers (Livros Digitais)
Número de Páginas 132 (aproximado)
Idioma 337
Acabamento e-book
Territorialidade Internacional
Formato Livro Digital Pdf
Gratuito Não
Proteção Drm Sim
Tamanho do Arquivo 6859
Início da Venda 30/11/2016
Código do Formato Pdf
Cód. Barras 9781615047352
Ano da Publicação 116
AutorWang,Jian-ying; Jaladanki,Rao N.